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The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars ret...

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars ret...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7b5abd175014310af73b55e18324022

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

About this item

Full title

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2016-05, Vol.5

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

Certain neuron types fire spontaneously at high rates, an ability that is crucial for their function in brain circuits. The spontaneously active GABAergic neurons of the substantia nigra pars reticulata (SNr), a major output of the basal ganglia, provide tonic inhibition of downstream brain areas. A depolarizing 'leak' current supports this firing...

Alternative Titles

Full title

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a7b5abd175014310af73b55e18324022

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7b5abd175014310af73b55e18324022

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.15271

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