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High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal...

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7bc352b5e9d473f9b3b201fba7c47d9

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue

About this item

Full title

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2024-04, Vol.15 (1), p.3475-17, Article 3475

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Somatic copy number alterations (SCNAs) are pervasive in advanced human cancers, but their prevalence and spatial distribution in early-stage, localized tumors and their surrounding normal tissues are poorly characterized. Here, we perform multi-region, single-cell DNA sequencing to characterize the SCNA landscape across tumor-rich and normal tissu...

Alternative Titles

Full title

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a7bc352b5e9d473f9b3b201fba7c47d9

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7bc352b5e9d473f9b3b201fba7c47d9

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-024-47664-z

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