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MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediate...

MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7f568f118f84e518080078bd6a978b4

MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy

About this item

Full title

MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy

Publisher

Warsaw: De Gruyter

Journal title

Open medicine (Warsaw, Poland), 2021-11, Vol.16 (1), p.1718-1727

Language

English

Formats

Publication information

Publisher

Warsaw: De Gruyter

More information

Scope and Contents

Contents

Mitophagy affects the activation of hepatic stellate cells (HSCs). Mitochondria-targeted ubiquinone (MitoQ) is a mitochondria-targeted antioxidant that reduces the production of intracellular reactive oxygen species (ROS). However, its relationship with mitophagy remains unclear. This study evaluated mitophagy during HSC activation and the effects...

Alternative Titles

Full title

MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a7f568f118f84e518080078bd6a978b4

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7f568f118f84e518080078bd6a978b4

Other Identifiers

ISSN

2391-5463

E-ISSN

2391-5463

DOI

10.1515/med-2021-0394

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