Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neuron...
Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons
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Publisher
England: eLife Sciences Publications Ltd
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Language
English
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Publisher
England: eLife Sciences Publications Ltd
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Contents
Despite mounting evidence that the mammalian retina is exceptionally reliant on proper NAD
+
homeostasis for health and function, the specific roles of subcellular NAD
+
pools in retinal development, maintenance, and disease remain obscure. Here, we show that deletion of the nuclear-localized NAD
+
synthase nicotinamide mononucleo...
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Full title
Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates development and early survival of retinal neurons
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TN_cdi_doaj_primary_oai_doaj_org_article_a7fa7f4bb4f44504ae3e7542438b2627
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a7fa7f4bb4f44504ae3e7542438b2627
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.71185
