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Mechanical control of innate immune responses against viral infection revealed in a human lung alveo...

Mechanical control of innate immune responses against viral infection revealed in a human lung alveo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8197b35fe0e4313b281435e947641eb

Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip

About this item

Full title

Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2022-04, Vol.13 (1), p.1928-17, Article 1928

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mechanical breathing motions have a fundamental function in lung development and disease, but little is known about how they contribute to host innate immunity. Here we use a human lung alveolus chip that experiences cyclic breathing-like deformations to investigate whether physical forces influence innate immune responses to viral infection. Influ...

Alternative Titles

Full title

Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a8197b35fe0e4313b281435e947641eb

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8197b35fe0e4313b281435e947641eb

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-022-29562-4

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