Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression
Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression
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Cambridge: eLife Sciences Publications Ltd
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Language
English
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Cambridge: eLife Sciences Publications Ltd
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N
1
-methylation of G37 is required for a subset of tRNAs to maintain the translational reading-frame. While loss of m
1
G37 increases ribosomal +1 frameshifting, whether it incurs additional translational defects is unknown. Here, we address this question by applying ribosome profiling to gain a genome-wide view of the effects of m
...
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Full title
Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression
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TN_cdi_doaj_primary_oai_doaj_org_article_a833a1e94d0c41389028df927ab81e6b
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a833a1e94d0c41389028df927ab81e6b
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.70619
