Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphob...
Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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Cytosine arabinoside (Ara‐C) is one of the key drugs for the treatment of acute myeloid leukemia. It is also used for consolidation therapy of acute lymphoblastic leukemia (ALL). Ara‐C is a deoxyadenosine analog and is phosphorylated to form cytosine arabinoside triphosphate (Ara‐CTP) as an active form. In the first step of the metabolic pathway, A...
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Clofarabine exerts antileukemic activity against cytarabine‐resistant B‐cell precursor acute lymphoblastic leukemia with low deoxycytidine kinase expression
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TN_cdi_doaj_primary_oai_doaj_org_article_a854096ebe964816b364a64b5f2d7ffa
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a854096ebe964816b364a64b5f2d7ffa
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2045-7634
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2045-7634
DOI
10.1002/cam4.1323