Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis
Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Arginase is an enzyme that converts L-arginine to urea and L-ornithine, an essential substrate for the polyamine pathway supporting Leishmania (Leishmania) amazonensis replication and its survival in the mammalian host. L-arginine is also the substrate of macrophage nitric oxide synthase 2 (NOS2) to produce nitric oxide (NO) that kills the parasite...
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Full title
Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis
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TN_cdi_doaj_primary_oai_doaj_org_article_a87f79f8e1104e07a0b80ee33b3660f0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a87f79f8e1104e07a0b80ee33b3660f0
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0187186
