Differential cardiotoxic electrocardiographic response to doxorubicin treatment in conscious versus...
Differential cardiotoxic electrocardiographic response to doxorubicin treatment in conscious versus anesthetized mice
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Publisher
United States: John Wiley & Sons, Inc
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Language
English
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Publisher
United States: John Wiley & Sons, Inc
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Contents
Introduction
Doxorubicin (DOX), an anticancer drug used in chemotherapy, causes significant cardiotoxicity. This study aimed to investigate the effects of DOX on mouse cardiac electrophysiology, in conscious versus anesthetized state.
Methods
Male and female C57BL/6 mice were injected with saline, 20 or 30 mg/kg DOX. ECGs were recorded 5 d...
Alternative Titles
Full title
Differential cardiotoxic electrocardiographic response to doxorubicin treatment in conscious versus anesthetized mice
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TN_cdi_doaj_primary_oai_doaj_org_article_a8aaff9e3db2441ea41cfc468f949b9f
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8aaff9e3db2441ea41cfc468f949b9f
Other Identifiers
E-ISSN
2051-817X
DOI
10.14814/phy2.14987
