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Virtual Screening in the Identification of Sirtuins’ Activity Modulators

Virtual Screening in the Identification of Sirtuins’ Activity Modulators

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8fa609434774dfd9b50125394a15288

Virtual Screening in the Identification of Sirtuins’ Activity Modulators

About this item

Full title

Virtual Screening in the Identification of Sirtuins’ Activity Modulators

Publisher

Basel: MDPI AG

Journal title

Molecules (Basel, Switzerland), 2022-09, Vol.27 (17), p.5641

Language

English

Formats

Publication information

Publisher

Basel: MDPI AG

More information

Scope and Contents

Contents

Sirtuins are NAD+-dependent deac(et)ylases with different subcellular localization. The sirtuins’ family is composed of seven members, named SIRT-1 to SIRT-7. Their substrates include histones and also an increasing number of different proteins. Sirtuins regulate a wide range of different processes, ranging from transcription to metabolism to genom...

Alternative Titles

Full title

Virtual Screening in the Identification of Sirtuins’ Activity Modulators

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a8fa609434774dfd9b50125394a15288

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a8fa609434774dfd9b50125394a15288

Other Identifiers

ISSN

1420-3049

E-ISSN

1420-3049

DOI

10.3390/molecules27175641

How to access this item