Tanshinones induce tumor cell apoptosis via directly targeting FHIT
Tanshinones induce tumor cell apoptosis via directly targeting FHIT
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Author / Creator
Zhou, Xianglian , Pan, Yuting , Wang, Yue , Wang, Bojun , Yan, Yu , Qu, Yi and Ke, Xisong
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The liposoluble tanshinones are bioactive components in
Salvia miltiorrhiza
and are widely investigated as anti-cancer agents, while the molecular mechanism is to be clarified. In the present study, we identified that the human fragile histidine triad (FHIT) protein is a direct binding protein of sodium tanshinone IIA sulfonate (STS), a water...
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Full title
Tanshinones induce tumor cell apoptosis via directly targeting FHIT
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TN_cdi_doaj_primary_oai_doaj_org_article_a9338087c3bd4153b81525e4508586f1
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a9338087c3bd4153b81525e4508586f1
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-91708-z