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Tanshinones induce tumor cell apoptosis via directly targeting FHIT

Tanshinones induce tumor cell apoptosis via directly targeting FHIT

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a9338087c3bd4153b81525e4508586f1

Tanshinones induce tumor cell apoptosis via directly targeting FHIT

About this item

Full title

Tanshinones induce tumor cell apoptosis via directly targeting FHIT

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2021-06, Vol.11 (1), p.12217-12217, Article 12217

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The liposoluble tanshinones are bioactive components in
Salvia miltiorrhiza
and are widely investigated as anti-cancer agents, while the molecular mechanism is to be clarified. In the present study, we identified that the human fragile histidine triad (FHIT) protein is a direct binding protein of sodium tanshinone IIA sulfonate (STS), a water...

Alternative Titles

Full title

Tanshinones induce tumor cell apoptosis via directly targeting FHIT

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a9338087c3bd4153b81525e4508586f1

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a9338087c3bd4153b81525e4508586f1

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-021-91708-z

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