Development of mirror-image monobodies targeting the oncogenic BCR::ABL1 kinase
Development of mirror-image monobodies targeting the oncogenic BCR::ABL1 kinase
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Mirror-image proteins, composed of
d
-amino acids, are an attractive therapeutic modality, as they exhibit high metabolic stability and lack immunogenicity. Development of mirror-image binding proteins is achieved through chemical synthesis of
d
-target proteins, phage display library selection of
l
-binders and chemical synthesis...
Alternative Titles
Full title
Development of mirror-image monobodies targeting the oncogenic BCR::ABL1 kinase
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a94e9c2c9c8d495c80cae1346c9eb306
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a94e9c2c9c8d495c80cae1346c9eb306
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-54901-y
