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Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermato...

Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermato...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a972f60ee2a743bdb9c238dbdd0ce726

Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction

About this item

Full title

Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction

Publisher

England: BioMed Central Ltd

Journal title

Cell communication and signaling, 2025-01, Vol.23 (1), p.58-21, Article 58

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Ionizing radiation (IR) poses a significant threat to male fertility by inducing substantial changes in the testis, yet the mechanisms underlying IR-induced spermatogenesis disorders remain poorly understood, necessitating the development of more effective radioprotective agents.
We employed Bulk RNA-seq and single-cell RNA-seq (scRNA-seq) on Ba...

Alternative Titles

Full title

Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_a972f60ee2a743bdb9c238dbdd0ce726

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a972f60ee2a743bdb9c238dbdd0ce726

Other Identifiers

ISSN

1478-811X

E-ISSN

1478-811X

DOI

10.1186/s12964-025-02067-5

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