Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermato...
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction
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Zhou, Hongjian , Xu, Zhipeng , Jiang, Chun , Wu, Qiuyue , Zhang, Chuanyue , Liu, Zhenyu , Zhang, Xiaoxue , Li, Weiwei , Pang, Yujia , Zhang, Jing , Pan, Wenju , Chen, Min and Xia, Xinyi
Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Ionizing radiation (IR) poses a significant threat to male fertility by inducing substantial changes in the testis, yet the mechanisms underlying IR-induced spermatogenesis disorders remain poorly understood, necessitating the development of more effective radioprotective agents.
We employed Bulk RNA-seq and single-cell RNA-seq (scRNA-seq) on Ba...
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Full title
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction
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TN_cdi_doaj_primary_oai_doaj_org_article_a972f60ee2a743bdb9c238dbdd0ce726
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a972f60ee2a743bdb9c238dbdd0ce726
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ISSN
1478-811X
E-ISSN
1478-811X
DOI
10.1186/s12964-025-02067-5