Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and ap...
Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis
About this item
Full title
Author / Creator
Pallares Robles, Alejandro , ten Cate, Vincent , Schulz, Andreas , Prochaska, Jürgen H. , Rapp, Steffen , Koeck, Thomas , Panova-Noeva, Marina , Heitmeier, Stefan , Schwers, Stephan , Leineweber, Kirsten , Seyfarth, Hans-Jürgen , Opitz, Christian F. , Spronk, Henri , Espinola-Klein, Christine , Lackner, Karl J. , Münzel, Thomas , Andrade-Navarro, Miguel A. , Konstantinides, Stavros V. , ten Cate, Hugo and Wild, Philipp S.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Animal experiments and early phase human trials suggest that inhibition of factor XIa (FXIa) safely prevents venous thromboembolism (VTE), and specific murine models of sepsis have shown potential efficacy in alleviating cytokine storm. These latter findings support the role of FXI beyond coagulation. Here, we combine targeted proteomics, machine l...
Alternative Titles
Full title
Association of FXI activity with thrombo-inflammation, extracellular matrix, lipid metabolism and apoptosis in venous thrombosis
Authors, Artists and Contributors
Author / Creator
ten Cate, Vincent
Schulz, Andreas
Prochaska, Jürgen H.
Rapp, Steffen
Koeck, Thomas
Panova-Noeva, Marina
Heitmeier, Stefan
Schwers, Stephan
Leineweber, Kirsten
Seyfarth, Hans-Jürgen
Opitz, Christian F.
Spronk, Henri
Espinola-Klein, Christine
Lackner, Karl J.
Münzel, Thomas
Andrade-Navarro, Miguel A.
Konstantinides, Stavros V.
ten Cate, Hugo
Wild, Philipp S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a98f6fd0075b490c99854a9f91f37b80
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a98f6fd0075b490c99854a9f91f37b80
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-022-13174-5
