Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apop...
Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apoptosis of tumor cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Anti-PD1 immunotherapy, as a single agent or in combination with standard chemotherapies, has significantly improved the outcome of many patients with cancers. However, resistance to anti-PD1 antibodies often decreases the long-term therapeutic benefits. Despite this observation in clinical practice, the molecular mechanisms associated with resista...
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Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apoptosis of tumor cells
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TN_cdi_doaj_primary_oai_doaj_org_article_a9df5a188ee4453c9e09d42ff5c0c69d
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a9df5a188ee4453c9e09d42ff5c0c69d
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-020-03224-z
