Multi-Modal Design, Synthesis, and Biological Evaluation of Novel Fusidic Acid Derivatives
Multi-Modal Design, Synthesis, and Biological Evaluation of Novel Fusidic Acid Derivatives
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Author / Creator
Wang, Luqi , Geng, Zhiyuan , Liu, Yuhang , Cao, Linhui , Liu, Yao , Zhang, Hourui , Bi, Yi and Lu, Jing
Publisher
Switzerland: MDPI AG
Journal title
Language
English
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Publisher
Switzerland: MDPI AG
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Scope and Contents
Contents
Fusidic acid (FA), a tetracyclic triterpenoid, has been approved to treat methicillin-resistant Staphylococcus aureus (MRSA) infections. However, there are few reports about FA derivatives with high efficacy superior to FA, manifesting the difficulty of discovering the derivatives based on experience-based drug design. In this study, we employed a...
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Full title
Multi-Modal Design, Synthesis, and Biological Evaluation of Novel Fusidic Acid Derivatives
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_a9f57e8bf9324d94a3379836d34880cc
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_a9f57e8bf9324d94a3379836d34880cc
Other Identifiers
ISSN
1420-3049
E-ISSN
1420-3049
DOI
10.3390/molecules30091983
