A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Herpes simplex virus 1 (HSV-1) is responsible for herpes simplex virus encephalitis (HSE), associated with a 70% mortality rate in the absence of treatment. Despite intravenous treatment with acyclovir, mortality remains significant, highlighting the need for new anti-herpetic agents. Herein, we describe a novel neurovirulent recombinant HSV-1 (rHS...
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Full title
A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
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TN_cdi_doaj_primary_oai_doaj_org_article_aa32d81874b94e47b48bcca576dc80a1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aa32d81874b94e47b48bcca576dc80a1
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-021-98047-z
