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Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function

Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aa32f3d7e38046868ba58a51eb9e8d12

Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Hearing relies on mechanically gated ion channels present in the actin‐rich stereocilia bundles at the apical surface of cochlear hair cells. Our knowledge of the mechanisms underlying the formation and maintenance of the sound‐receptive structure is limited. Utilizing a large‐scale forward genetic screen in mice, genome mapping and gene complement...

Alternative Titles

Full title

Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_aa32f3d7e38046868ba58a51eb9e8d12

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aa32f3d7e38046868ba58a51eb9e8d12

Other Identifiers

ISSN

1757-4676

E-ISSN

1757-4684

DOI

10.15252/emmm.201910288

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