MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based...
MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Cryo electron tomography (cryo-ET) allows observing macromolecular complexes in their native environment. The common routine of subtomogram averaging (STA) allows obtaining the three-dimensional (3D) structure of abundant macromolecular complexes, and can be coupled with discrete classification to reveal conformational heterogeneity of the sample....
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MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations
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TN_cdi_doaj_primary_oai_doaj_org_article_aa9c6eb282f24cbdaac3cbb9da277b47
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aa9c6eb282f24cbdaac3cbb9da277b47
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-37037-9