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MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based...

MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aa9c6eb282f24cbdaac3cbb9da277b47

MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations

About this item

Full title

MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2023-06, Vol.13 (1), p.10596-10596, Article 10596

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Cryo electron tomography (cryo-ET) allows observing macromolecular complexes in their native environment. The common routine of subtomogram averaging (STA) allows obtaining the three-dimensional (3D) structure of abundant macromolecular complexes, and can be coupled with discrete classification to reveal conformational heterogeneity of the sample....

Alternative Titles

Full title

MDTOMO method for continuous conformational variability analysis in cryo electron subtomograms based on molecular dynamics simulations

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_aa9c6eb282f24cbdaac3cbb9da277b47

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aa9c6eb282f24cbdaac3cbb9da277b47

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-023-37037-9

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