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Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair

Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aae698efdb56403c8aba30b80d3ec197

Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair

About this item

Full title

Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2023-08, Vol.14 (1), p.5104-5104, Article 5104

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Histone post-translational modifications promote a chromatin environment that controls transcription, DNA replication and repair, but surprisingly few phosphorylations have been documented. We report the discovery of histone H3 serine-57 phosphorylation (H3S57ph) and show that it is implicated in different DNA repair pathways from fungi to vertebra...

Alternative Titles

Full title

Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_aae698efdb56403c8aba30b80d3ec197

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aae698efdb56403c8aba30b80d3ec197

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-023-40843-4

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