A novel biosensor to study cAMP dynamics in cilia and flagella
A novel biosensor to study cAMP dynamics in cilia and flagella
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England: eLife Science Publications, Ltd
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Language
English
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Publisher
England: eLife Science Publications, Ltd
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Contents
The cellular messenger cAMP regulates multiple cellular functions, including signaling in cilia and flagella. The cAMP dynamics in these subcellular compartments are ill-defined. We introduce a novel FRET-based cAMP biosensor with nanomolar sensitivity that is out of reach for other sensors. To measure cAMP dynamics in the sperm flagellum, we gener...
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Full title
A novel biosensor to study cAMP dynamics in cilia and flagella
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TN_cdi_doaj_primary_oai_doaj_org_article_aaf3386b6d7b47d1b78fa1f71fd7c228
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aaf3386b6d7b47d1b78fa1f71fd7c228
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.14052