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A novel biosensor to study cAMP dynamics in cilia and flagella

A novel biosensor to study cAMP dynamics in cilia and flagella

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aaf3386b6d7b47d1b78fa1f71fd7c228

A novel biosensor to study cAMP dynamics in cilia and flagella

About this item

Full title

A novel biosensor to study cAMP dynamics in cilia and flagella

Publisher

England: eLife Science Publications, Ltd

Journal title

eLife, 2016-03, Vol.5

Language

English

Formats

Publication information

Publisher

England: eLife Science Publications, Ltd

More information

Scope and Contents

Contents

The cellular messenger cAMP regulates multiple cellular functions, including signaling in cilia and flagella. The cAMP dynamics in these subcellular compartments are ill-defined. We introduce a novel FRET-based cAMP biosensor with nanomolar sensitivity that is out of reach for other sensors. To measure cAMP dynamics in the sperm flagellum, we gener...

Alternative Titles

Full title

A novel biosensor to study cAMP dynamics in cilia and flagella

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_aaf3386b6d7b47d1b78fa1f71fd7c228

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aaf3386b6d7b47d1b78fa1f71fd7c228

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.14052

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