Apolipoprotein E4 interferes with lipid metabolism to exacerbate depression‐like behaviors in 5xFAD...
Apolipoprotein E4 interferes with lipid metabolism to exacerbate depression‐like behaviors in 5xFAD mice
About this item
Full title
Author / Creator
Gong, Yanju , Li, Mingfeng , Liu, Min , Wu, Xinghan , Li, Yanhong , Qin, Chuan and Zhang, Ling
Publisher
United States: John Wiley & Sons, Inc
Journal title
Language
English
Formats
Publication information
Publisher
United States: John Wiley & Sons, Inc
Subjects
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Scope and Contents
Contents
Background
Apolipoprotein E4 (ApoE4) allele is the strongest genetic risk factor for late‐onset Alzheimer's disease, and it can aggravate depressive symptoms in non‐AD patients. However, the impact of ApoE4 on AD‐associated depression‐like behaviors and its underlying pathogenic mechanisms remain unclear.
Methods
This study developed a 5xF...
Alternative Titles
Full title
Apolipoprotein E4 interferes with lipid metabolism to exacerbate depression‐like behaviors in 5xFAD mice
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_aafee32291554212bbe8b373ecb6376c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aafee32291554212bbe8b373ecb6376c
Other Identifiers
ISSN
2576-2095,2096-5451
E-ISSN
2576-2095
DOI
10.1002/ame2.12446
