Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma
Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma
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England: BioMed Central Ltd
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English
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England: BioMed Central Ltd
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Asthma is a chronic respiratory condition, with airway hyperresponsiveness (AHR) and inflammation as hallmarks. The hypothesis that the substantially increased expression of arginase 1 in activated macrophages limits the availability of L-arginine for nitric oxide synthesis, and thus increases AHR in lungs of mice with experimentally induced allerg...
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Full title
Hypoargininemia exacerbates airway hyperresponsiveness in a mouse model of asthma
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TN_cdi_doaj_primary_oai_doaj_org_article_ab910cb740604b42a6b9457946b3188e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ab910cb740604b42a6b9457946b3188e
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ISSN
1465-993X,1465-9921
E-ISSN
1465-993X,1465-9921
DOI
10.1186/s12931-018-0809-9
