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Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_abf8c7f4da7a45d4af0d1631fd583659

Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

About this item

Full title

Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2021-04, Vol.12 (1), p.2057-15, Article 2057

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lipocalin 2 (LCN2) was recently identified as an endogenous ligand of the type 4 melanocortin receptor (MC4R), a critical regulator of appetite. However, it remains unknown if this molecule influences appetite during cancer cachexia, a devastating clinical entity characterized by decreased nutrition and progressive wasting. We demonstrate that LCN2...

Alternative Titles

Full title

Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_abf8c7f4da7a45d4af0d1631fd583659

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_abf8c7f4da7a45d4af0d1631fd583659

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/s41467-021-22361-3

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