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Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated...

Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ac5fe1c845034ffaaf2ea4ec623f9cee

Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

About this item

Full title

Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

Publisher

England: BioMed Central Ltd

Journal title

Journal of translational medicine, 2010-07, Vol.8 (1), p.74-74, Article 74

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Familial Amyloidotic Polyneuropathy (FAP) is a disorder characterized by the extracellular deposition of fibrillar Transthyretin (TTR) amyloid, with a special involvement of the peripheral nerve. We had previously shown that doxycycline administered for 3 months at 40 mg/Kg/ml in the drinking water, was capable of removing TTR amyloid deposits pres...

Alternative Titles

Full title

Synergy of combined Doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ac5fe1c845034ffaaf2ea4ec623f9cee

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ac5fe1c845034ffaaf2ea4ec623f9cee

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/1479-5876-8-74

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