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Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ac99edb139cf49b3ad842ac3b0879ae8

Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

About this item

Full title

Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-05, Vol.8 (1), p.8225-12, Article 8225

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lupus nephritis is a crucial complication of systemic lupus erythematosus. In this study, we investigated the roles of mouse natural killer T (NKT) cells in lupus nephritis. From 24 weeks of age, NZB/NZW F1 mice were injected with alpha-galactosylceramide (α-GalCer) or vehicle once a week for four weeks. In the α-GalCer group, the levels of protein...

Alternative Titles

Full title

Repeated administration of alpha-galactosylceramide ameliorates experimental lupus nephritis in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ac99edb139cf49b3ad842ac3b0879ae8

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ac99edb139cf49b3ad842ac3b0879ae8

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-26470-w

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