BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin ex...
BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling
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Author / Creator
Shaashua, Lee , Ben-Shmuel, Aviad , Pevsner-Fischer, Meirav , Friedman, Gil , Levi-Galibov, Oshrat , Nandakumar, Subhiksha , Barki, Debra , Nevo, Reinat , Brown, Lauren E. , Zhang, Wenhan , Stein, Yaniv , Lior, Chen , Kim, Han Sang , Bojmar, Linda , Jarnagin, William R. , Lecomte, Nicolas , Mayer, Shimrit , Stok, Roni , Bishara, Hend , Hamodi, Rawand , Levy-Lahad, Ephrat , Golan, Talia , Porco, John A. , Iacobuzio-Donahue, Christine A. , Schultz, Nikolaus , Tuveson, David A. , Lyden, David , Kelsen, David and Scherz-Shouval, Ruth
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Tumors initiate by mutations in cancer cells, and progress through interactions of the cancer cells with non-malignant cells of the tumor microenvironment. Major players in the tumor microenvironment are cancer-associated fibroblasts (CAFs), which support tumor malignancy, and comprise up to 90% of the tumor mass in pancreatic cancer. CAFs are tran...
Alternative Titles
Full title
BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling
Authors, Artists and Contributors
Author / Creator
Ben-Shmuel, Aviad
Pevsner-Fischer, Meirav
Friedman, Gil
Levi-Galibov, Oshrat
Nandakumar, Subhiksha
Barki, Debra
Nevo, Reinat
Brown, Lauren E.
Zhang, Wenhan
Stein, Yaniv
Lior, Chen
Kim, Han Sang
Bojmar, Linda
Jarnagin, William R.
Lecomte, Nicolas
Mayer, Shimrit
Stok, Roni
Bishara, Hend
Hamodi, Rawand
Levy-Lahad, Ephrat
Golan, Talia
Porco, John A.
Iacobuzio-Donahue, Christine A.
Schultz, Nikolaus
Tuveson, David A.
Lyden, David
Kelsen, David
Scherz-Shouval, Ruth
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Primary Identifiers
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TN_cdi_doaj_primary_oai_doaj_org_article_ace9d26882394fbe81d1eae2056e5de9
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ace9d26882394fbe81d1eae2056e5de9
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-34081-3
