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IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers

IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ad4809f736484197a181c829b8bf3a50

IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers

About this item

Full title

IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers

Publisher

England: BioMed Central

Journal title

Journal of translational medicine, 2024-07, Vol.22 (1), p.642-14, Article 642

Language

English

Formats

Publication information

Publisher

England: BioMed Central

More information

Scope and Contents

Contents

Oncogenic mutations in the RAS gene are associated with uncontrolled cell growth, a hallmark feature contributing to tumorigenesis. While diverse therapeutic strategies have been diligently applied to treat RAS-mutant cancers, successful targeting of the RAS gene remains a persistent challenge in the field of cancer therapy. In our study, we discov...

Alternative Titles

Full title

IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_ad4809f736484197a181c829b8bf3a50

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ad4809f736484197a181c829b8bf3a50

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-024-05384-4

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