Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer ce...
Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formation
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Author / Creator
Xu, Feifei , Zhang, Jialu , Hu, Guolin , Liu, Lei and Liang, Weijiang
Publisher
England: BioMed Central
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Language
English
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Publication information
Publisher
England: BioMed Central
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Scope and Contents
Contents
Intra-tumoral hypoxia and increases in extracellular level of transforming growth factor β1 (TGF-β1), which are common findings in cancer, are associated with an increased risk of metastasis and mortality. Moreover, metastasis is the leading cause of death of patients with cervical cancer. PLOD2 is an intracellular enzyme required for the biogenesi...
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Full title
Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formation
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ad67401a8ce241d095790a7479aa4a3b
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ad67401a8ce241d095790a7479aa4a3b
Other Identifiers
ISSN
1475-2867
E-ISSN
1475-2867
DOI
10.1186/s12935-017-0420-z
