Anoctamin 1 controls bone resorption by coupling Cl− channel activation with RANKL-RANK signaling tr...
Anoctamin 1 controls bone resorption by coupling Cl− channel activation with RANKL-RANK signaling transduction
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Author / Creator
Sun, Weijia , Guo, Shuai , Li, Yuheng , Li, JianWei , Liu, Caizhi , Chen, Yafei , Wang, Xuzhao , Tan, Yingjun , Tian, Hua , Wang, Cheng , Du, Ruikai , Zhong, Guohui , Shi, Sai , Ma, Biao , Qu, Chang , Fu, Jingxuan , Jin, Xiaoyan , Zhao, Dingsheng , Zhan, Yong , Ling, Shukuan , An, Hailong and Li, Yingxian
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Osteoclast over-activation leads to bone loss and chloride homeostasis is fundamental importance for osteoclast function. The calcium-activated chloride channel Anoctamin 1 (also known as TMEM16A) is an important chloride channel involved in many physiological processes. However, its role in osteoclast remains unresolved. Here, we identified the ex...
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Anoctamin 1 controls bone resorption by coupling Cl− channel activation with RANKL-RANK signaling transduction
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TN_cdi_doaj_primary_oai_doaj_org_article_ad9a828c99b74de39cdca2c41f2000f0
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ad9a828c99b74de39cdca2c41f2000f0
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-022-30625-9
