MLKL-mediated necroptosis is a target for cardiac protection in mouse models of type-1 diabetes
MLKL-mediated necroptosis is a target for cardiac protection in mouse models of type-1 diabetes
About this item
Full title
Author / Creator
Cao, Ting , Ni, Rui , Ding, Weimin , Ji, Xiaoyun , Li, Lan , Liao, Guangneng , Lu, Yanrong , Fan, Guo-Chang , Zhang, Zhuxu and Peng, Tianqing
Publisher
London: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Background Cardiomyocyte death contributes to cardiac pathology of diabetes. Studies have shown that the RIPK3/MLKL necroptosis signaling is activated in diabetic hearts. Deletion of RIPK3 was reported to attenuate myocardial injury and heart dysfunction in streptozocin (STZ)-induced diabetic mice, suggesting a potential role of necroptosis in diab...
Alternative Titles
Full title
MLKL-mediated necroptosis is a target for cardiac protection in mouse models of type-1 diabetes
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_ada2e978445144918d77f081a979c81e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ada2e978445144918d77f081a979c81e
Other Identifiers
ISSN
1475-2840
E-ISSN
1475-2840
DOI
10.1186/s12933-022-01602-9
