Glucose transporter 1 critically controls microglial activation through facilitating glycolysis
Glucose transporter 1 critically controls microglial activation through facilitating glycolysis
About this item
Full title
Author / Creator
Wang, Luxi , Pavlou, Sofia , Du, Xuan , Bhuckory, Mohajeet , Xu, Heping and Chen, Mei
Publisher
England: BioMed Central Ltd
Journal title
Language
English
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Publication information
Publisher
England: BioMed Central Ltd
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Scope and Contents
Contents
Uncontrolled microglial activation contributes to the pathogenesis of various neurodegenerative diseases. Previous studies have shown that proinflammatory microglia are powered by glycolysis, which relays on high levels of glucose uptake. This study aimed to understand how glucose uptake is facilitated in active microglia and whether microglial act...
Alternative Titles
Full title
Glucose transporter 1 critically controls microglial activation through facilitating glycolysis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_add78c81cb8349c6a0d6cd29476f9933
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_add78c81cb8349c6a0d6cd29476f9933
Other Identifiers
ISSN
1750-1326
E-ISSN
1750-1326
DOI
10.1186/s13024-019-0305-9
