Identifying lupus Patient Subsets Through Immune Cell Deconvolution of Gene Expression Data in Two A...
Identifying lupus Patient Subsets Through Immune Cell Deconvolution of Gene Expression Data in Two Atacicept Phase II Studies
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Atlanta: John Wiley & Sons, Inc
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English
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Atlanta: John Wiley & Sons, Inc
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Objective: To use cell‐based gene signatures to identify patients with systemic lupus erythematous (SLE) in the phase II/III APRIL–SLE and phase IIb ADDRESS II trials most likely to respond to atacicept. Methods: A published immune cell deconvolution algorithm based on Affymetrix gene array data was applied to whole blood gene expression from patie...
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Identifying lupus Patient Subsets Through Immune Cell Deconvolution of Gene Expression Data in Two Atacicept Phase II Studies
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TN_cdi_doaj_primary_oai_doaj_org_article_add9fe7b98494705a1bf88c69bce3eb1
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_add9fe7b98494705a1bf88c69bce3eb1
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ISSN
2578-5745
E-ISSN
2578-5745
DOI
10.1002/acr2.11594