Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex di...
Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction
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Author / Creator
Fontana, Camilla Maria , Terrin, Francesca , Facchinello, Nicola , Meneghetti, Giacomo , Dinarello, Alberto , Gambarotto, Lisa , Zuccarotto, Annalisa , Caichiolo, Micol , Brocca, Ginevra , Verin, Ranieri , Nazio, Francesca , Carnevali, Oliana , Cecconi, Francesco , Bonaldo, Paolo and Dalla Valle, Luisa
Publisher
England: BioMed Central
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Language
English
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Publisher
England: BioMed Central
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Contents
AMBRA1 is an intrinsically disordered protein, working as a scaffold molecule to coordinate, by protein-protein interaction, many cellular processes, including autophagy, mitophagy, apoptosis and cell cycle progression. The zebrafish genome contains two ambra1 paralogous genes (a and b), both involved in development and expressed at high levels in...
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Full title
Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction
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TN_cdi_doaj_primary_oai_doaj_org_article_ae5216e6d4bf45f9a757c2b8eedd7f2d
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ae5216e6d4bf45f9a757c2b8eedd7f2d
Other Identifiers
ISSN
0717-6287,0716-9760
E-ISSN
0717-6287
DOI
10.1186/s40659-023-00430-9
