LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis
LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis
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Author / Creator
Wang, Jing , Chai, Qiyao , Lei, Zehui , Wang, Yiru , He, Jiehua , Ge, Pupu , Lu, Zhe , Qiang, Lihua , Zhao, Dongdong , Yu, Shanshan , Qiu, Changgen , Zhong, Yanzhao , Li, Bing-Xi , Zhang, Lingqiang , Pang, Yu , Gao, George Fu and Liu, Cui Hua
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Chronic infections, including
Mycobacterium tuberculosis
(Mtb)-caused tuberculosis (TB), can induce host immune exhaustion. However, the key checkpoint molecules involved in this process and the underlying regulatory mechanisms remain largely undefined, which impede the application of checkpoint-based immunotherapy in infectious diseases. Her...
Alternative Titles
Full title
LILRB1-HLA-G axis defines a checkpoint driving natural killer cell exhaustion in tuberculosis
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TN_cdi_doaj_primary_oai_doaj_org_article_ae6f6b1e577e473187f3a8bfd0f24742
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_ae6f6b1e577e473187f3a8bfd0f24742
Other Identifiers
ISSN
1757-4684,1757-4676
E-ISSN
1757-4684
DOI
10.1038/s44321-024-00106-1
