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Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis

Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aead2be3b597492993095c0c6cef9667

Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis

About this item

Full title

Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2024-07, Vol.7 (1), p.892-12, Article 892

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Bone is a highly dynamic tissue undergoing continuous formation and resorption. Here, we investigated differential but complementary roles of hypoxia-inducible factor (HIF)-1α and HIF-2α in regulating bone remodeling. Using RNA-seq analysis, we identified that specific genes involved in regulating osteoblast differentiation were similarly but sligh...

Alternative Titles

Full title

Differential but complementary roles of HIF-1α and HIF-2α in the regulation of bone homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_aead2be3b597492993095c0c6cef9667

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aead2be3b597492993095c0c6cef9667

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-024-06581-z

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