Optimized RT-qPCR and a novel normalization method for validating circulating miRNA biomarkers in ag...
Optimized RT-qPCR and a novel normalization method for validating circulating miRNA biomarkers in ageing-related diseases
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Circulating miRNAs have potential as minimally invasive biomarkers for diagnosing various diseases, including ageing-related disorders such as Alzheimer’s disease (AD). However, the lack of standardization in the common analysis method, RT-qPCR, and specifically in the normalization step, has resulted in inconsistent data across studies, hindering...
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Optimized RT-qPCR and a novel normalization method for validating circulating miRNA biomarkers in ageing-related diseases
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TN_cdi_doaj_primary_oai_doaj_org_article_aee6d7077508426092283d6fd5bba37a
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_aee6d7077508426092283d6fd5bba37a
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-023-47971-3
