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Leveraging CAR macrophages targeting c-Met for precision immunotherapy in pancreatic cancer: insight...

Leveraging CAR macrophages targeting c-Met for precision immunotherapy in pancreatic cancer: insight...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af06c2ded9ba41a3b57bd338e4dc5a32

Leveraging CAR macrophages targeting c-Met for precision immunotherapy in pancreatic cancer: insights from single-cell multi-omics

About this item

Full title

Leveraging CAR macrophages targeting c-Met for precision immunotherapy in pancreatic cancer: insights from single-cell multi-omics

Publisher

England: Springer

Journal title

Molecular Medicine, 2024-11, Vol.30 (1), p.231-17, Article 231

Language

English

Formats

Publication information

Publisher

England: Springer

More information

Scope and Contents

Contents

Pancreatic cancer is known for its poor prognosis and resistance to conventional therapies, largely due to the presence of cancer stem cells (CSCs) and aggressive angiogenesis. Effectively targeting these CSCs and associated angiogenic pathways is crucial for effective treatment. This study leverages single-cell multi-omics to explore a novel thera...

Alternative Titles

Full title

Leveraging CAR macrophages targeting c-Met for precision immunotherapy in pancreatic cancer: insights from single-cell multi-omics

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_af06c2ded9ba41a3b57bd338e4dc5a32

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af06c2ded9ba41a3b57bd338e4dc5a32

Other Identifiers

ISSN

1528-3658,1076-1551

E-ISSN

1528-3658

DOI

10.1186/s10020-024-00996-4

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