SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition b...
SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Sex-determining region Y-box2 (SOX2), a master regulator of embryonic and induced pluripotent stem cells, drives cancer stem cells (CSCs) properties, fuels tumor initiation, and contributes to tumor aggressiveness. Our previous study has demonstrated the oncogenic role of SOX2 in colorectal cancer (CRC). In this study, we sought to elucidate the un...
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SOX2 promotes chemoresistance, cancer stem cells properties, and epithelial–mesenchymal transition by β-catenin and Beclin1/autophagy signaling in colorectal cancer
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TN_cdi_doaj_primary_oai_doaj_org_article_af0e54769cd24e458803227f8ea439e6
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af0e54769cd24e458803227f8ea439e6
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-021-03733-5
