PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
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Author / Creator
Searcy, Madeline B. , Larsen, Randolph K. , Stevens, Bradley T. , Zhang, Yang , Jin, Hongjian , Drummond, Catherine J. , Langdon, Casey G. , Gadek, Katherine E. , Vuong, Kyna , Reed, Kristin B. , Garcia, Matthew R. , Xu, Beisi , Kimbrough, Darden W. , Adkins, Grace E. , Djekidel, Nadhir , Porter, Shaina N. , Schreiner, Patrick A. , Pruett-Miller, Shondra M. , Abraham, Brian J. , Rehg, Jerold E. and Hatley, Mark E.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Fusion-positive rhabdomyosarcoma (FP-RMS) driven by the expression of the PAX3-FOXO1 (P3F) fusion oncoprotein is an aggressive subtype of pediatric rhabdomyosarcoma. FP-RMS histologically resembles developing muscle yet occurs throughout the body in areas devoid of skeletal muscle highlighting that FP-RMS is not derived from an exclusively myogenic...
Alternative Titles
Full title
PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors
Authors, Artists and Contributors
Author / Creator
Larsen, Randolph K.
Stevens, Bradley T.
Zhang, Yang
Jin, Hongjian
Drummond, Catherine J.
Langdon, Casey G.
Gadek, Katherine E.
Vuong, Kyna
Reed, Kristin B.
Garcia, Matthew R.
Xu, Beisi
Kimbrough, Darden W.
Adkins, Grace E.
Djekidel, Nadhir
Porter, Shaina N.
Schreiner, Patrick A.
Pruett-Miller, Shondra M.
Abraham, Brian J.
Rehg, Jerold E.
Hatley, Mark E.
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Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_af11c11b372b412d83edd57dfaac71cf
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af11c11b372b412d83edd57dfaac71cf
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-023-43044-1