Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types
About this item
Full title
Author / Creator
Mead, Benjamin E. , Ordovas-Montanes, Jose , Braun, Alexandra P. , Levy, Lauren E. , Bhargava, Prerna , Szucs, Matthew J. , Ammendolia, Dustin A. , MacMullan, Melanie A. , Yin, Xiaolei , Hughes, Travis K. , Wadsworth, Marc H. , Ahmad, Rushdy , Rakoff-Nahoum, Seth , Carr, Steven A. , Langer, Robert , Collins, James J. , Shalek, Alex K. and Karp, Jeffrey M.
Publisher
England: BioMed Central Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central Ltd
Subjects
More information
Scope and Contents
Contents
Single-cell genomic methods now provide unprecedented resolution for characterizing the component cell types and states of tissues such as the epithelial subsets of the gastrointestinal tract. Nevertheless, functional studies of these subsets at scale require faithful in vitro models of identified in vivo biology. While intestinal organoids have be...
Alternative Titles
Full title
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types
Authors, Artists and Contributors
Author / Creator
Ordovas-Montanes, Jose
Braun, Alexandra P.
Levy, Lauren E.
Bhargava, Prerna
Szucs, Matthew J.
Ammendolia, Dustin A.
MacMullan, Melanie A.
Yin, Xiaolei
Hughes, Travis K.
Wadsworth, Marc H.
Ahmad, Rushdy
Rakoff-Nahoum, Seth
Carr, Steven A.
Langer, Robert
Collins, James J.
Shalek, Alex K.
Karp, Jeffrey M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_af6abd99fa9b45318eb28d7964c53335
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af6abd99fa9b45318eb28d7964c53335
Other Identifiers
ISSN
1741-7007
E-ISSN
1741-7007
DOI
10.1186/s12915-018-0527-2
