An essential role for TASL in mouse autoimmune pathogenesis and Toll-like receptor signaling
An essential role for TASL in mouse autoimmune pathogenesis and Toll-like receptor signaling
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
TASL is an immune adaptor that binds to the solute carrier SLC15A4 and facilitates activation of the transcription factor IRF5 during Toll-like receptor (TLR) signaling. Similar to
IRF5
and
SLC15A4
, single nucleotide polymorphisms (SNPs) within
TASL
have been implicated in increased susceptibility to systemic lupus erythematosus...
Alternative Titles
Full title
An essential role for TASL in mouse autoimmune pathogenesis and Toll-like receptor signaling
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_doaj_primary_oai_doaj_org_article_af6ca7ac882943998a6fc3ccaf23006c
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af6ca7ac882943998a6fc3ccaf23006c
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-024-55690-0