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RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance

RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af72e0ed2bf34fe08603e87cd561159e

RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance

About this item

Full title

RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance

Publisher

England: BioMed Central Ltd

Journal title

BMC cancer, 2018-11, Vol.18 (1), p.1158-1158, Article 1158

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Rearrangements of the anaplastic lymphoma kinase (ALK) belong to the promising targets in the therapy of advanced non-small cell lung cancer (NSCLC) and are predominantly detected by immunohistochemistry (IHC) and/or fluorescence in-situ hybridization (FISH). However, both methods occasionally produce discordant results, especially in so-called bor...

Alternative Titles

Full title

RNA-based analysis of ALK fusions in non-small cell lung cancer cases showing IHC/FISH discordance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_af72e0ed2bf34fe08603e87cd561159e

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af72e0ed2bf34fe08603e87cd561159e

Other Identifiers

ISSN

1471-2407

E-ISSN

1471-2407

DOI

10.1186/s12885-018-5070-6

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