Role of PI3K/Akt-Mediated Nrf2/HO-1 Signaling Pathway in Resveratrol Alleviation of Zearalenone-Indu...
Role of PI3K/Akt-Mediated Nrf2/HO-1 Signaling Pathway in Resveratrol Alleviation of Zearalenone-Induced Oxidative Stress and Apoptosis in TM4 Cells
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Author / Creator
Xu, Wenlin , Zheng, Hao , Fu, Youtian , Gu, Yayi , Zou, Hui , Yuan, Yan , Gu, Jianhong , Liu, Zongping and Bian, Jianchun
Publisher
Switzerland: MDPI AG
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English
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Publisher
Switzerland: MDPI AG
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Contents
Zearalenone (ZEA) is a common mycotoxin that induces oxidative stress (OS) and affects the male reproductive system in animals. Resveratrol (RSV) has good antioxidant activity and can activate nuclear factor erythroid 2-related factor (Nrf2) to protect cells through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway....
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Full title
Role of PI3K/Akt-Mediated Nrf2/HO-1 Signaling Pathway in Resveratrol Alleviation of Zearalenone-Induced Oxidative Stress and Apoptosis in TM4 Cells
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TN_cdi_doaj_primary_oai_doaj_org_article_af76a29ae7444c61b088691383dfc109
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af76a29ae7444c61b088691383dfc109
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ISSN
2072-6651
E-ISSN
2072-6651
DOI
10.3390/toxins14110733