Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in p...
Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Environmental and epigenetic factors often play an important role in polygenic disorders. However, how such factors affect disease-specific tissues at the molecular level remains to be understood. Here, we address this in pulmonary arterial hypertension (PAH). We obtain pulmonary arterial endothelial cells (PAECs) from lungs of patients and control...
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Full title
Remodeling of active endothelial enhancers is associated with aberrant gene-regulatory networks in pulmonary arterial hypertension
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TN_cdi_doaj_primary_oai_doaj_org_article_af8f51e6fdcf4006aee980f4873bd8eb
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af8f51e6fdcf4006aee980f4873bd8eb
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-020-15463-x
