The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The single nucleotide polymorphism (SNP) rs744373 in the bridging integrator-1 gene (BIN1) is a risk factor for Alzheimer’s disease (AD). In the brain, BIN1 is involved in endocytosis and sustaining cytoskeleton integrity. Post-mortem and in vitro studies suggest that BIN1-associated AD risk is mediated by increased tau pathology but whether rs7443...
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The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory
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TN_cdi_doaj_primary_oai_doaj_org_article_af9ef677104b492a9ea299f7988cef93
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_af9ef677104b492a9ea299f7988cef93
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/s41467-019-09564-5
