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Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_afd221fdbb4c475bbda925ce0c8607b0

Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

About this item

Full title

Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

Publisher

England: eLife Sciences Publications Ltd

Journal title

eLife, 2019-10, Vol.8

Language

English

Formats

Publication information

Publisher

England: eLife Sciences Publications Ltd

More information

Scope and Contents

Contents

Identifying neurons that have functional opioid receptors is fundamental for the understanding of the cellular, synaptic and systems actions of opioids. Current techniques are limited to post hoc analyses of fixed tissues. Here we developed a fluorescent probe, naltrexamine-acylimidazole (NAI), to label opioid receptors based on a chemical approach...

Alternative Titles

Full title

Visualizing endogenous opioid receptors in living neurons using ligand-directed chemistry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_afd221fdbb4c475bbda925ce0c8607b0

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_afd221fdbb4c475bbda925ce0c8607b0

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.49319

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