Association of region‐specific hippocampal reduction of neurogranin with inflammasome proteins in po...
Association of region‐specific hippocampal reduction of neurogranin with inflammasome proteins in post mortem brains of Alzheimer's disease
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Author / Creator
Vontell, Regina T. , Gober, Ryan , Dallmeier, Julian , Brzostowicki, Daniel , Barreda, Ayled , Blennow, Kaj , Zetterberg, Henrik , Kvartsberg, Hlin , Gultekin, Sakir Humayun , Rivero Vaccari, Juan Pablo , Bramlett, Helen M. , Dietrich, W. Dalton , Keane, Robert W. , Davis, David A. , Rundek, Tatjana and Sun, Xiaoyan
Publisher
United States: John Wiley and Sons Inc
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Language
English
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Publisher
United States: John Wiley and Sons Inc
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Contents
INTRODUCTION
Neurogranin (Ng) is considered a biomarker for synaptic dysfunction in Alzheimer's disease (AD). In contrast, the inflammasome complex has been shown to exacerbate AD pathology.
METHODS
We investigated the protein expression, morphological differences of Ng, and correlated Ng to hyperphosphorylated tau in the post mortem brain...
Alternative Titles
Full title
Association of region‐specific hippocampal reduction of neurogranin with inflammasome proteins in post mortem brains of Alzheimer's disease
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TN_cdi_doaj_primary_oai_doaj_org_article_b004ddac02d747e7a1752bb243a63c79
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b004ddac02d747e7a1752bb243a63c79
Other Identifiers
ISSN
2352-8737
E-ISSN
2352-8737
DOI
10.1002/trc2.12444
