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Tumor suppressor Par-4 activates autophagy-dependent ferroptosis

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b042898b09fd4d3082a06ae086a75503

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis

About this item

Full title

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis

Publisher

London: Nature Publishing Group UK

Journal title

Communications biology, 2024-06, Vol.7 (1), p.732-17, Article 732

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Ferroptosis is a unique iron-dependent form of non-apoptotic cell death characterized by devastating lipid peroxidation. Whilst growing evidence suggests that ferroptosis is a type of autophagy-dependent cell death, the underlying molecular mechanisms regulating ferroptosis are largely unknown. In this study, through an unbiased RNA-sequencing scre...

Alternative Titles

Full title

Tumor suppressor Par-4 activates autophagy-dependent ferroptosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_doaj_primary_oai_doaj_org_article_b042898b09fd4d3082a06ae086a75503

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b042898b09fd4d3082a06ae086a75503

Other Identifiers

ISSN

2399-3642

E-ISSN

2399-3642

DOI

10.1038/s42003-024-06430-z

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