Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
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Author / Creator
Kaczmarek-Hajek, Karina , Zhang, Jiong , Kopp, Robin , Grosche, Antje , Rissiek, Björn , Saul, Anika , Bruzzone, Santina , Engel, Tobias , Jooss, Tina , Krautloher, Anna , Schuster, Stefanie , Magnus, Tim , Stadelmann, Christine , Sirko, Swetlana , Koch-Nolte, Friedrich , Eulenburg, Volker and Nicke, Annette
Publisher
England: eLife Science Publications, Ltd
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English
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Publisher
England: eLife Science Publications, Ltd
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Contents
The P2X7 channel is involved in the pathogenesis of various CNS diseases. An increasing number of studies suggest its presence in neurons where its putative functions remain controversial for more than a decade. To resolve this issue and to provide a model for analysis of P2X7 functions, we generated P2X7 BAC transgenic mice that allow visualizatio...
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Full title
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody
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TN_cdi_doaj_primary_oai_doaj_org_article_b062997e054c49a3929a6f440c8b1a7e
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_doaj_primary_oai_doaj_org_article_b062997e054c49a3929a6f440c8b1a7e
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ISSN
2050-084X
E-ISSN
2050-084X
DOI
10.7554/eLife.36217
